hiar loss research

Monday, January 30, 2012

 

Women and Minoxidil for Hair Loss

Many women can experience diffused hair loss. It may first be noticeable along partings or in a general overall thinning of the hair. The FDA has approved minoxidil as a medication to restore hair in women and men. A thorough evaluation by one of Los Angeles top hair restoration doctors is highly recommended. This assures a woman suffering from hair loss the opportunity to undertake the best course of action to resolve it.

Parsa Mohebi Reviews Women and minoxidil

Minoxidil unlike finasteride could be used in women with hair loss to increase the bulk of hair and prevent further hair loss. Only the 2% concentration of minoxidil is approved for use in women. Women are generally more sensitive to the side effects of minoxidil in decreasing blood pressure (hypotension). The allergic reaction to this medication is also more common. Facial hair could occasionally be seen in women who use minoxidil for the treatment of their hair loss. Limiting the application of medication carefully to the scalp can prevent this side effect. It has also been found that the drug can be passed from a mother to a child via breast milk.

Dr. Mohebi is the medical director at Los Angeles hair restoration clinics throughout southern California. US Hair Restoration’s newest office is opening in Bakersfield, California.

Thursday, October 22, 2009

Alopecia Totalis

I know a twenty-something woman with alopecia totalis who contacted a California hair transplant center. This disease is more widespread than many realize. People who have it can live normal, happy lives, although they may stand out in a crowd. Since my friend acquired alopecia totalis, lots of people have told her they know someone with the disease.

There are more people than we know who have alopecia totalis as a cause of hair loss, like professional basketball player Charlie Villanueva. Although they don't look the same as other people, if they learn to overcome their self-doubts they can be rather successful people.

She'd describe her situation this way: I'm still in my twenties and I know I haven't experienced the more serious consequences of alopecia totalis. I'm determined to maintain a positive attitude and I believe I will even later on in life. There's a lot more to a man or woman than their hair style. In fact, maybe having alopecia totalis will help us focus more on our character and integrity than superficial appearances. If I had the choice of being bald and fit, or with a full head of hair and obese, I choose the former. I want to be a good steward of my physical body.

She has a wonderful attitude! Alopecia Universalis (AU) treatment can be complex and sometimes not even possible. If she paid a visit to my office and met some of my patients, she'd be dumbfounded by how saddened they feel at the loss of their hair. There are many hair restoration forums and online communities that bring the patients with alopecia universalis together.

Something I always tell my patients is that it is OK to want to look good physically. I say if it's possible for a person to change their appearance (as people do it every day with laser hair removal and Botox treatments) in a way that's socially acceptable, then do it. But if it's something that can't be altered, you must believe God made you that way for a reason, and what separates us physically are what make us unique.

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Saturday, November 22, 2008

Dr. Parsa Mohebi, is the medical director of US Hair Restoration and a researcher on different topics such as hair loss and wound healing has been active in hair loss and hair restoration research.

Hair cloning or multiplication is progressing fact. The result of another hair cloning study that was recently published. This article on hair cloning (multiplication) was just got published titled “Formation of Hair Structures Suitable for Implantation”. Intercytex was in charge of this study as the other series of hair multiplication of hair cloning studies. Hair multiplication, also known as Hair multiplication, has been discussed in Hair Restoration Blog in many posts and has been the subject of many studies in the past. Intercytex is one of the companies that have been reporting some progress in different levels of the study and have reported that they have finished phase II and are starting phase III of this study.

The hair restoration research has shown that hair cloning through culturing hair cells has been successful in animals and it is now being studied on humans. The following article tries to elucidate the process of hair multiplication on laboratory animals that were released.

The goal of this hair multiplication study was “to develop a construct through which implanted follicular cells will efficiently cause hair regeneration for the treatment of androgenetic alopecia.” They used follicular dermal and epidermal cells isolated from embryonic mouse skin which were formed into aggregates.

The cellular aggregates were kept and incubated in lab in culture for five to seven days and then implanted inside the skin into athymic mice, which does not have the capability of rejecting foreign tissue. They observed that during culturing, mixed cell aggregates developed into hair-like structures, termed “proto-hairs.” Proto-hairs contained structures that resembled normal hair components, such as dermal papillae, hair matrix and rudimentary hair shafts.

The researchers implanted into mouse skin, they developed further into mature hair follicles capable of prolonged growth. The authors concluded that mixed aggregates of murine follicular cells have the ability to develop while in culture into proto-hairs that retains the ability to fully develop into hair follicles after implantation.

Proto-hairs from human hair stem cells could provide a convenient and practical means by which follicular cells could be implanted for efficient hair regeneration to treat hair loss. Although the study does not add to what we knew before, it elucidates the process of work for the other scientists who follow on the progress of hair multiplication (cloning) research.

US Hair Restoration California offices are involved and follow the progress of hair multiplication studies precisely. Dr. Mohebi is active in some hair multiplication studies. The results will be released and published in medical literature when they are available.



Thursday, August 14, 2008

Hair Cloning – Hair Culturing – Hair Multiplication
One of the companies that area working on hair cloning is Intercytex that has recently released a research result on the hair multiplication experiments in the journal of experimental dermatology.
Hair cell multiplication can also be a revolution in hair transplant surgery field. Follicular cell implantation in this article is reviewed and mentioned as an experimental cell therapy for the treatment of hair loss that uses cultured hair follicles or their cells to induce new hair formation. The process of multiplying hair cells is based on the demonstration that adult dermal papilla cells (DPC) retain the hair inductive potential that they acquired during hair morphogenesis before birth. To harvest FCI, the researchers could isolate hair active cells from scalp biopsies and then grow them in cultures in order to make adequate cells to generate several other follicles from a few.
The big question is “when will hair cloning be available”. The article goes over what has been done so far for hair multiplication experimentally. Intercytex group has been involved and developed some hair stem cell, hair culturing and hair multiplication projects. Some of those methods could be used for the treatment of hair loss. Some of those known as hair cloning are also being done by other organizations or universities.
Following expansion of cells in culture, they implanted those cells into the scalp where they induce the formation of new follicles below the level of skin. They describe a consistent, reliable method in which they can test hair induction. Since the process relies on the ability to retain the potential for hair induction during the expansion of DPC in culture.
They reviewed a simple graft model that supports hair morphogenesis. In this experiment, they combine dermal cells with embryonic mouse epidermis that provides the keratinocyte (one of the skin cells) component of induced follicles. The grafts are placed under a protective skin flap in the host mouse where the cells will make a skin graft that can produce hair if the dermal cells are hair producing DPC.
By using the system of freshly isolated and cultured mouse embryo dermal cells as well as cultured dermal papilla cells from other species we can make new hair that could be used of hair restoration in people with baldness.
The best thing about this process was that the induced hairs were aesthetically indistinguishable from those of the epidermal donor in length, thickness, and pigmentation. The investigators stated that the newly formed hairs were considered normal and could resemble a complete natural hair after microscopic examination.
Our hair transplant team at Los Angeles hair transplant surgery centers of US Hair Restoration will closely follow up with the progress of hair multiplication and cloning techniques. Although the result of the cultured hair on animals has been released before, the current published article is very interesting and can elucidates more on the characteristics of multiplied and newly formed hair quality during the process of hair multiplication so called hair cloning. It seems like we still have a long way to go until we can practically use hair multiplication techniques in restoring human hair. The good thing is that it cannot be kept a secret when hair multiplication technology is available.

Saturday, April 19, 2008

Dr. Mohebi and psychology of hair transplant
One of the local Los Angeles Magazines just published an article titled “Treat your depression with hair transplant”. Yes, it is true and is based on the new released result of Dr. Mohebi’s study on psychology of hair transplant. Dr. Mohebi is medical director of US Hair Restoration. Dr. Parsa Mohebi is a fellowship trained hair restoration surgeon. He finished his hair restoration surgery fellowship with Dr. William Rassman, one true pioneer of modern hair transplant techniques.
Dr. Mohebi has studied in depth different psycho-social aspects of men who undergo hair transplant surgery for treatment of their hair loss. Dr. Mohebi has performed several other studies on the techniques of hair restoration. Dr. Parsa Mohebi is a performing hair restoration surgery in his Encino office in Los Angeles California.
Dr. Mohebi uses follicular unit transplantation for the best cosmetic result. Dr. Mohebi is a true believer of “being bald is an option now”. The goal of Dr. Mohebi and his experienced team is restoring more than just hair. Their quality hair transplant surgeries have returned hope to many men who are suffering from hair loss and its emotional scars.

Friday, April 11, 2008

Dr. Pars Mohebi Performs Mega session hair transplant surgery at Los Angeles US Hair Restoration Surgery. Mega session hair transplant surgery has been around for almost a decade since Dr. Rassman and others started doing bigger and bigger sessions. Before 1993 all could be done was less than 1000 and occasionally 1500 grafts per each session. Using newer techniques and larger team of experienced technicians, we at US Hair Restoration are currently performing large sessions on a regular basis.
Dr. Mohebi is a fellowship trained hair restoration surgeon. Not all physician teams are equal. If a doctor routinely performs sessions in over 2500 graft size, then it would be safe to assume that this doctor has mastered the skills required for large session. Unfortunately, not all doctors have either the teams or the skills to accomplish the feat on a routine basis. Limiting the size of the session to under 2000 grafts, it may take more surgical sessions to accomplish the same goal as when twice the number is transplanted.
Many factors should come together for a megasession hair transplant surgery. First, the surgical team must be trained in doing large sessions with fast, efficient cutting and placing. The following points must be available for the surgery to be successful. The sessions should not take more than eight to ten hours, for more than that, the grafts that are out of the body awaiting placement produces reduced graft growth. Hair transplant surgeon should keep a larger team of technicians to help reducing the time of surgery.
The surgeon must know the nuances of prolonged anesthesia without increasing the risks to the patient. The patient’s scalp laxity must be very loose so that a wide strip can be taken safely (often these strips measure greater than 2cm in width and 22cm in length). The patient’s density must be high (50% higher than normal densities). Large sessions might carry increased risk of swelling and redness after surgery, but overall are not more risky than smaller sessions, but the above criteria must be bet or the yield would not be there. At US Hair Restoration, we offer megasessions to patients with extensive baldness with good donor quality with excellent results.

Wednesday, April 02, 2008

US Hair Restoration - Male pattern baldness

US Hair Restoration - Male pattern baldness: "Causes of Baldness in Men

Dihydrotestosterone (DHT) a powerful sex hormone is known to be the cause for male pattern baldness. It has been noted that men with MPB have elevated levels of the enzyme 5-alpha-reductase. The act of genes, hormones and time makes prone hair shorter and finer over time and before it eventually dies out. The progress of this miniaturization causes disappearance of certain hair shafts and shrinkage of the others. In this process the scalp hair becomes very fine and short, which is also known as miniaturized hair.

Balding can begin as early as the end of puberty. The Hamilton-Norwood scale is used for the classification of male pattern baldness and is based on the progress and severity of hair loss. Currently, several treatment options are available. Besides hair transplantation, there are two medications that have been FDA approved for use in the United States. Patients who benefit the most from effects of medications on slowing the baldness process are still in the initial stages of baldness." Extracted from the website of US Hair Restoration.